Zingerone Targets Status Epilepticus by Blocking Hippocampal Neurodegeneration via Regulation of Redox Imbalance, Inflammation and Apoptosis
نویسندگان
چکیده
منابع مشابه
RU486 Mitigates Hippocampal Pathology Following Status Epilepticus
Status epilepticus (SE) induces rapid hyper-activation of the hypothalamo-pituitary-adrenocortical (HPA) axis. HPA axis hyperactivity results in excess exposure to high levels of circulating glucocorticoids, which are associated with neurotoxicity and depression-like behavior. These observations have led to the hypothesis that HPA axis dysfunction may exacerbate SE-induced brain injury. To test...
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ژورنال
عنوان ژورنال: Pharmaceuticals
سال: 2021
ISSN: 1424-8247
DOI: 10.3390/ph14020146